Laithwaite’s flagship wine store makes up part of the 2.3-acre bar, restaurant, wine tasting and retail centre near London Bridge.
Andrew Stead, director of digital and communications at Laithwaite’s, told OLN: “It is of course a shame to see the capital lose a flagship venue for wine-related education and entertainment.
“Our shop will be open for the foreseeable future, business as usual, as the location facing the back of Borough Market brings us lots of footfall.
“Being so central is also perfect for managing corporate accounts in the city and makes a handy location for customer events.”
Vinopolis was founded 16 years ago as a centre for wine enthusiasts, but managing director Samantha Anderson said the wine experience “has been challenging over the years” and that closing the venue was “the best possible decision for shareholders”.