The translucent metallic bottle has been released in time for World AIDS Day on December 1.
It has an rrp of £34.50 and half the profits go to Red’s global fund to fight HIV and AIDS.
Charles Gibb, president of Belvedere Vodka, said: “Our passion for philanthropy led to the creation of Belvedere Red last year and our commitment to helping Red and the global health community achieve the first AIDS-free generation by 2015 has not wavered since.
“The new bottle design is symbolic of our dedication to Red and a sign to our audience that we, collectively as a global community, can put an end to mother-to-child transmission of this deadly disease but only with their support.”
Contributions from sales of Belvedere Red have so far provided more than 2 million days of medicine that keeps HIV patients healthy and allows them to deliver HIV-free babies.
To mark World AIDs Day on December 1, Belvedere Red will be sampled at the Whole Foods High Street Kensington store, where a 250-litre bottle currently dominates the Christmas window.