The decision was made by mutual agreement after both parties decided that the Douro-based
quinta was in "an excellent position to stand alone".
The changes follow the completion of new high-tech wine making facilities in one of historic buildings of the estate.
The new team at Quinta de Roriz will be lead by Cristiano van Zeller and Sandra Tavares da Silva, who will be taking over gradually from the existing Symington Family's team, and will be in full control from July.
Euan Mackay has been appointed sales director of Symington Family Estates. Mackay, who will be based in Portugal, will report to commercial director Johnny Symington. In 1996 Mackay joined Symington Family Estates with responsibility for several key European and Asian markets, but remained based in the UK. In 2006 he moved to Oporto with his family.