The voluntary initiative, which takes effect in the six-week run-up to Christmas, also includes refusing to serve people who are suspected of creating drink-related problems in the Cambourne area.
Partners and Communities Together, the group behind the scheme, involves police, the town council and church leaders.
Police will be offering support to off-licence staff to help them identify drunks, troublemakers and people who are buying alcohol on behalf of children.
Neighbourhood beat manager PC Ben Charity said: “I am delighted that through the PACT process, the community of Camborne and many of its leaders have worked together to find common ground on measures to tackle the relatively small amount of people who act anti-socially on the streets and open spaces of Camborne, and in doing so adversely affect the lives of the many.
“We will be supporting these measures, and in particular we will be supporting the off-licence holders who have admirably come together as one on this issue.”