Production will be transferred to
the Murphy's brewery, also in Cork. Around 120 employees will be made redundant, but the brewing giant
the Beamish brand w ould continue.
Corporate affairs manager Declan Farmer said: " We do not foresee any problems with having two stouts in the portfolio,
any more than having five lagers."
Gerrit van Loo, managing director of Heineken Ireland, said: "Retaining two breweries is not sustainable and the loss of so many jobs remains a sad but unavoidable outcome."
Heineken gained control of the Beamish brewery in October following a six-month investigation by Ireland's Competition Authority. It ruled that it wouldn't be a conflict of interest for Heineken to produce both Beamish and Murphy's.
Scottish & Newcastle UK, which was acquired by Heineken in April,
is to take over responsibility for Murphy's stout from Inbev UK. S&N will be responsible for the UK brewing, marketing and distribution rights
from February 2009.