Flagship brands Echo Falls, Kumala and Hardys will split the break-bumper sponsorship, which will run for seven months from June 1, between them – starting with Echo Falls.
The show features four complete strangers who each host a dinner party and judge one another's cooking and hosting skills, and is one of Channel 4's best-loved programmes.
Consumer marketing vice president Clare Griffiths said: "We are very excited about this sponsorship and the opportunity it offers us to really bring our brands to life at point of purchase.
"The show is classed as must-see viewing due to its relevance to the current climate, and as such has vast appeal across several of our key consumer segments. Just like the show, all three brands that we have chosen to showcase are well-known and well-loved by UK consumers, making them a great fit with this engaging, entertaining show."
Constellation is backing the TV sponsorship with a through-the-line marketing campaign including in-store activity and brand-specific promotions in key outlets.
Off Licence News is running its own version of Come Dine With Me to raise cash for the Benevolent.
Come Wine With Me will see generic wine bodies including Wines of Chile, Wines of South Africa and New Zealand Winegrowers pit their culinary and wine-pairing skills against one another, on June 5 – the Benevolent's first fundraising day.